Speaker
Prof.
Jaroslav Ilnytskyi
(Yukhnovskii Institute for Condensed Matter Physics of the National Academy of Sciences of Ukraine, Lviv, Ukraine; Lviv Polytechnic National University, Lviv, Ukraine)
Description
Excessive concentration of the low density lipoproteins (LDLs) in blood increases the risk of cardiovascular diseases. One of the strategies to reduce its contents is the hemoperfusion therapy, when LDLs are selectively retracted by an external adsorber located outside the patient body. Recently, a photo-controllable smart surface was developed characterized by high selectivity and repeated cyclic usage. We examine the efficiency of such setup via computer simulation of a mesoscopic models for both LDL and the azobenzene-containing polymer brush. It is found that the adsorption efficiency is seriously affected by the brush microstructure, with the bunch-like (bush-like) arrangement of its constituent chains being the most efficient.
Primary authors
Prof.
Jaroslav Ilnytskyi
(Yukhnovskii Institute for Condensed Matter Physics of the National Academy of Sciences of Ukraine, Lviv, Ukraine; Lviv Polytechnic National University, Lviv, Ukraine)
Dmytro Yaremchuk
(Lviv Polytechnic National University, Lviv, Ukraine)
Orest Komarytsia
(Danylo Halytskyi Lviv Medical University, Lviv, Ukraine)
