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SUMMARY:Quasi-Linkage Equilibrium in spatially separated populations and i
 n diploid genetics
DTSTART;VALUE=DATE-TIME:20260922T082000Z
DTEND;VALUE=DATE-TIME:20260922T085000Z
DTSTAMP;VALUE=DATE-TIME:20260914T013616Z
UID:indico-contribution-525@indico.bitp.kiev.ua
DESCRIPTION:Speakers: Erik Aurell (Department of Computational Science and
  Technology\, KTH-Royal Institute of Technology\, AlbaNova University Cent
 er)\nQuasi-Linkage Equilibrium (QLE) is a theory developed by Kimura (1965
 ) and Neher & Shraiman (2009:2011) to explain the emergency of distributio
 ns of genotypes in a population akin to the canonical ensemble in statisti
 cal physics\, referred to as a QLE state. Recombination (exchange of genet
 ic material between individuals) acts analogously to molecular collisions 
 in kinetic gas theory\, and leads\, if strong enough\, to relaxation to an
  equilibrium-like state\, for a review\, see [1].\n\nGeographic isolation 
 is important in evolution\, it is a driving force behind speciation. I wil
 l discuss how recombination interacts with migration between spatially iso
 lated sub-populations\, and if the QLE state can coexist with migration. I
  will also consider the setting where different sub-populations live in di
 fferent environments with different fitness landscapes\, and if one can in
 fer those landscapes from the population structures if individuals can mov
 e between the populations [2]. I will also discuss the conceptual issue if
  the assumption of haploid genomes usually made in the literature is only 
 a simplification or if the evolution of diploid populations is qualitative
 ly different and can lead to other phases than QLE.\n\n[1] "Statistical ge
 netics in and out of quasi-linkage equilibrium"\, V Dichio\, HL Zeng\, E A
 urell\, Reports on Progress in Physics 86 (5)\, 052601 (2023)\n[2]  "Fitne
 ss Inference in Presence of Migrations between Coupled Evolving Population
 s"\, YH Huang\, B Dumont\, HL Zeng\, J Barton\, E Aurell (2026)\, arXiv pr
 eprint arXiv:2605.22665\n\nhttps://indico.bitp.kiev.ua/event/18/contributi
 ons/525/
LOCATION:Bogolyubov Institute for Theoretical Physics Conference Hall
URL:https://indico.bitp.kiev.ua/event/18/contributions/525/
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